IONTAS’ management have published high impact research papers on many core technology advances in antibody drug discovery.

39 Results Found

A comprehensive search of functional sequence space using large mammalian display libraries created by gene editing

Publication: mAbs. June 2019. doi:10.1080/19420862.2019.1618673 PMID: 31107136.

Authors: Parthiban K, Perera RL, Sattar M, Huang Y, Masters E, Griffiths D, Surade S, Leah R, Dyson MR, McCafferty J

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In vivo neutralization of dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG antibodies

Publication: Nature Communications. October 2018. doi:10.1038/s41467-018-06086-4 PMID: 30279409.

Authors: Laustsen AH, Karatt-Vellatt A, Masters EW, Arias AS, Pus U, Knudsen C, Oscoz S, Slavny P, Griffiths DT, Luther AM, Leah RA, Lindholm M, Lomonte B, Gutiérrez JM, McCafferty J

Basics of Antibody Phage Display Technology

Publication: Toxins (Basel). June 2018. doi:10.3390/toxins10060236 PMID: 29890762.

Authors: Ledsgaard L, Kilstrup M, Karatt-Vellatt A, McCafferty J, Laustsen AH

Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from ligand binding domain

Publication: Scientific Reports. August 2017. PMID: 28827556.

Authors: DiCara DM, Chirgadze DY, Pope AR, Karatt-Vellat A, Winter A, Slavny P, van den Heuvel J, Parthiban K, Holland J, Packman LC, Birchmeier W, Gherardi E, McCafferty J

Fundamentals of Expression in Mammalian cells

Publication: Adv Exp Med Biol.. May 2016, 896 (217-24). PMID: 27165328.

Authors: Dyson MR