PEGS Boston

01-05 May 2017

Boston, MA

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Dr Mike Dyson will be presenting a paper on the 5th May at 11.35 concerning the "Construction and Usage of Large IgG Antibody Libraries in Mammalian Cells". The presentation decribes the integration of antibody genes into mammalian cells at a single genomic locus through the use of site-specific nucleases. the technlogy allows the generation of IgG antibody libraries consisting of many millions of clones. These libraries can subsequently be screened for expression and developability of the antibodies in conjunction to functional screening/reporting within the same cell.