European Antibody Congress

29-31 October 2018

Basel, Switzerland

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IONTAS will be attending the European Antibody Congress between the 29th - 31st April. 

Dr Mike Dyson (CTO) will be presenting his talk entitled "Mammalian display: antibody discovery, affinity maturation and developability screening in IgG format" The talk will describe the use of directed integration of antibody genes by CRISPR/Cas9 and TALE nucleases, to construct large libraries in mammalian cells containing a single antibody gene/cell. This permits construction of millions of monoclonal stable cell lines displaying IgG antibodies on their surface from which antibodies can be selected by flow cytometry for specificity, binding affinity, species cross-reactivity, developabilty and expression level.