Antibody Discovery

Our technologies offer the ability to mine large antibody repertoires to generate target specific antibodies with desired functionalities and biophysical properties. We provide the means to rapidly identify antibodies for different applications such as human therapy, animal health, pharmacokinetic and anti-drug antibodies assays, diagnostics, imaging and research. The discovery of antibodies from our technologies requires significant expertise in ensuring good quality antigens with native presentation, assay development (including cell based functional assays) and screening and characterisation regimes. Our scientific team is vastly experienced in building and screening phage and mammalian display libraries for fully human, rodents, rabbit, chicken, and llama antibodies. Based on Partner needs, we screen thousands of clones and identify antibodies to a desired target with pre-defined characteristics as relevant affinity, specificity, and species cross-reactivity

 

Deliverables (4-12 months):

Intermediate and final overview report

Clone overview with screening and sequence data

Purified IgG/ Fab/ scFv/ VHHs (0.1-1 mg) and Certificate of Analysis (CoA)

Characterisation overview